Hadros

Bioinformatics team with training in both computational genomics and molecular biology (Skoltech Life Sciences — Bioinformatics & Genomics / Cell & Molecular Biology tracks). We take your sequencing data from raw reads to biological insight.

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🔬 What We Can Help With

▸ Single-Cell & Spatial Omics
• scRNA-seq, scTCR/BCR-seq, CITE-seq, Visium, MERFISH
• QC, normalization, integration, clustering, differential expression
• Cell-type annotation, trajectory analysis, and multi-sample comparisons

▸ Immune Repertoire Analysis
• Clonotype assembly and diversity profiling
• Clonal expansion and repertoire sharing
• Antigen-associated clone detection and statistical testing

▸ Bulk Sequencing
• RNA-seq, ATAC-seq, ChIP-seq, 16S/shotgun metagenomics
• WGS/WES variant calling, annotation, and filtering
• Pathway and gene set enrichment analysis

▸ Statistical Modeling & Machine Learning
• Biomarker and gene signature discovery
• Classification models with cross-validation
• Feature selection, effect size estimation, and robust validation schemes

▸ Pipeline Development & Infrastructure
• Reproducible workflows in Nextflow and Snakemake
• Docker/Singularity containerization
• Deployment on HPC, on-premise systems, or cloud-connected environments
• Version-controlled, documented pipelines for internal reuse

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📦 Typical Deliverables
• QC summaries and analysis reports
• Publication-ready figures and statistical tables
• Documented scripts or notebooks
• Reproducible workflows for future use
• Interpretation support for research and R&D teams

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✅ Why Clients Work With Us
• We understand both the biology and the computation
• We build reproducible, well-documented analyses — not black-box outputs
• We communicate clearly with wet-lab scientists, computational teams, and technical stakeholders
• We work with defined milestones and practical delivery timelines